Find Research Outputs

2018

C-Jun N-terminal kinase 1 defective CD4+CD25+FoxP3+ cells prolong islet allograft survival in diabetic mice

Tripathi, D., Cheekatla, S. S., Paidipally, P., Radhakrishnan, R. K., Welch, E., Thandi, R. S., Tvinnereim, A. R. & Vankayalapati, R. Dec 1 2018 In : Scientific Reports. 8, 1, 3310

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 8
Islets of Langerhans
Allografts
Phosphotransferases
Liver

Disrupting the Btk pathway suppresses COPD-like lung alterations in atherosclerosis prone apoE-/-mice following regular exposure to cigarette smoke

Florence, J. M., Krupa, A., Booshehri, L. M., Gajewski, A. L. & Kurdowska, A. K. Feb 1 2018 In : International Journal of Molecular Sciences. 19, 2, 343

Research output: Contribution to journalArticle

emphysema
arteriosclerosis
disrupting
Pulmonary diseases
Tobacco Smoke Pollution

Disseminated actinomycetoma due to Nocardia wallacei

Welsh, O., Salinas-Carmona, M. C., Brown-Elliott, B. A., Smith, T., Cardenas-De La Garza, J. A. & Wallace, R. J. Jan 1 2018 (Accepted/In press) In : International Journal of Dermatology.

Research output: Contribution to journalArticle

Linezolid
Mycetoma
Nocardia
Aminoglycosides
Therapeutics

Gene editing as a promising approach for respiratory diseases

Bai, Y., Liu, Y., Su, Z., Ma, Y., Ren, C., Zhao, R. & Ji, H. L. Mar 1 2018 In : Journal of Medical Genetics. 55, 3, p. 143-149 7 p.

Research output: Contribution to journalArticle

CRISPR-Associated Proteins
Respiration
Genes
Sneezing
Pleural Cavity

Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals

Lee, K. H., Sulbarán, G., Yang, S., Mun, J. Y., Alamo, L., Pinto, A., Sato, O., Ikebe, M., Liu, X., Korn, E. D., Sarsoza, F., Bernstein, S. I., Padrón, R. & Craig, R. Feb 27 2018 In : Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. E1991-E2000

Research output: Contribution to journalArticle

myosin
animals
Schizosaccharomyces pombe
Amoeba
Porifera
1 Citations

Mycobacterium abscessus, a taxonomic puzzle

Tortoli, E., Kohl, T. A., Brown-Elliott, B. A., Trovato, A., Cardoso-Leão, S., Garcia, M. J., Vasireddy, S., Turenne, C. Y., Griffith, D. E., Philley, J. V., Niemann, S., Wallace, R. J. & Cirillo, D. M. Jan 1 2018 In : International Journal of Systematic and Evolutionary Microbiology. 68, 1, p. 467-469 3 p., 002457

Research output: Contribution to journalLetter

Mycobacterium abscessus
Bacterial Typing Techniques
16S Ribosomal RNA
Nontuberculous Mycobacteria
Bacterial DNA

Targeting plasminogen activator inhibitor-1 in tetracycline-induced pleural injury in rabbits

Florova, G., Azghani, A. O., Karandashova, S., Schaefer, C., Yarovoi, S. V., Declerck, P. J., Cines, D. B., Idell, S. & Komissarov, A. A. Jan 1 2018 In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 1, p. L54-L68

Research output: Contribution to journalArticle

saruplase
Plasminogen Activator Inhibitor 1
Thrombolytic Therapy
Tetracycline
Animal Models

The complexities of nocardia taxonomy and identification

Conville, P. S., Brown-Elliott, B. A., Smith, T. & Zelazny, A. M. Jan 1 2018 In : Journal of Clinical Microbiology. 56, 1, e01419

Research output: Contribution to journalArticle

Nocardia
Nocardia asteroides
Actinobacteria
Microbiology
History
2017
1 Citations

A community perspective on the inclusion of pregnant women in tuberculosis drug trials

McKenna, L., Frick, M., Lee, C., Namutamba, D., Smit, L., Theunissen, M., Vandevelde, W., Madoori, S., Snow, K. & Seaworth, B. Oct 1 2017 In : Clinical Infectious Diseases. 65, 8, p. 1383-1387 5 p.

Research output: Contribution to journalReview article

Pregnant Women
Tuberculosis
Research
Pharmaceutical Preparations
Ethics Committees
1 Citations

Activated full-length myosin-X moves processively on filopodia with large steps toward diverse two-dimensional directions

Sato, O., Jung, H. S., Komatsu, S., Tsukasaki, Y., Watanabe, T. M., Homma, K. & Ikebe, M. Mar 13 2017 In : Scientific Reports. 7, 44237

Research output: Contribution to journalArticle

Pseudopodia
Myosins
Actin Cytoskeleton
Actins
Leucine Zippers
2 Citations

Adipose fatty acid binding protein promotes saturated fatty acid-induced macrophage cell death through enhancing ceramide production

Yuwen, Z., Rao, E., Jun, Z., Hao, J., Sun, Y., Liu, S., Sauter, E. R., Bernlohr, D. A., Cleary, M. P., Suttles, J. & Li, B. Jan 15 2017 In : Journal of Immunology. 198, 2, p. 798-807 10 p.

Research output: Contribution to journalArticle

Fatty Acid-Binding Proteins
Ceramides
Cell Death
Fatty Acids
Macrophages
21 Citations

Adult Patients With Bronchiectasis: A First Look at the US Bronchiectasis Research Registry

Aksamit, T. R., O'Donnell, A. E., Barker, A., Olivier, K. N., Winthrop, K. L., Daniels, M. L. A., Johnson, M., Eden, E., Griffith, D., Knowles, M., Metersky, M., Salathe, M., Thomashow, B., Tino, G., Turino, G., Carretta, B., Daley, C. L., for the & Bronchiectasis Research Registry Consortium May 1 2017 In : Chest. 151, 5, p. 982-992 11 p.

Research output: Contribution to journalArticle

Bronchiectasis
Registries
Research
Demography
Kartagener Syndrome
2 Citations

AhR activation increases IL-2 production by alloreactive CD4+ T cells initiating the differentiation of mucosal-homing Tim3+Lag3+ Tr1 cells

Ehrlich, A. K., Pennington, J. M., Tilton, S., Wang, X., Marshall, N. B., Rohlman, D., Funatake, C., Punj, S., O'Donnell, E., Yu, Z., Kolluri, S. K. & Kerkvliet, N. I. 2017 (Accepted/In press) In : European Journal of Immunology.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Regulatory T-Lymphocytes
Interleukin-2
Cell Differentiation
T-Lymphocytes

A review of injectable and implantable biomaterials for treatment and repair of soft tissues in wound healing

Chou, S. F., Gunaseelan, S., Kiellani, M. H. H., Thottempudi, V. V. K., Neuenschwander, P. & Nie, H. 2017 In : Journal of Nanotechnology. 2017, 6341710

Research output: Contribution to journalReview article

Biocompatible Materials
Nanotechnology
Biomaterials
Repair
Tissue

A theory of eu-estrogenemia: A unifying concept

Turner, R. J. & Kerber, I. J. Sep 1 2017 In : Menopause. 24, 9, p. 1086-1097 12 p.

Research output: Contribution to journalReview article

Estrogens
Randomized Controlled Trials
Estrogen Receptors
Observational Studies
Ovariectomy

Bioequivalence of a Liquid Formulation of Alpha1-Proteinase Inhibitor Compared with Prolastin®-C (Lyophilized Alpha1-PI) in Alpha1-Antitrypsin Deficiency

Barker, A. F., Campos, M. A., Brantly, M. L., Stocks, J. M., Sandhaus, R. A., Lee, D., Steinmann, K., Lin, J. & Sorrells, S. Oct 5 2017 (Accepted/In press) In : COPD: Journal of Chronic Obstructive Pulmonary Disease. p. 1-7 7 p.

Research output: Contribution to journalArticle

alpha 1-Antitrypsin
Therapeutic Equivalency
Area Under Curve
Peptide Hydrolases
Least-Squares Analysis

Body fluid exosomes and cancer

Sauter, E. R. Oct 1 2017 In : Translational Cancer Research. 6, p. S1301-S1303

Research output: Contribution to journalEditorial

Exosomes
Body Fluids
Neoplasms
1 Citations

Boosting efferocytosis in alveolar space using BCG vaccine to protect host against influenza pneumonia

Mukherjee, S., Subramaniam, R., Chen, H., Smith, A., Keshava, S. & Shams, H. Jul 1 2017 In : PLoS ONE. 12, 7, e0180143

Research output: Contribution to journalArticle

BCG Vaccine
Mycobacterium bovis BCG
phagocytes
Bacilli
Phagocytes
4 Citations
Myosin-Light-Chain Phosphatase
Muscle Contraction
Smooth Muscle
Growth and Development
GTP-Binding Proteins
3 Citations

Early Secreted Antigenic Target of 6-kDa of Mycobacterium tuberculosis Stimulates IL-6 Production by Macrophages through Activation of STAT3

Jung, B. G., Wang, X., Yi, N., Ma, J., Turner, J. & Samten, B. Jan 20 2017 In : Scientific Reports. 7, 40984

Research output: Contribution to journalArticle

Macrophage Activation
Mycobacterium tuberculosis
Interleukin-6
Macrophages
Phosphorylation
10 Citations

Efficacy and safety of onabotulinumtoxinA therapy are sustained over 4 years of treatment in patients with neurogenic detrusor overactivity: Final results of a long-term extension study

Kennelly, M. , Dmochowski, R. , Schulte-Baukloh, H. , Ethans, K. , Del Popolo, G. , Moore, C. , Jenkins, B. , Guard, S. , Zheng, Y. , Karsenty, G. , Bolton, D. M. , Gardiner, R. A. , Horsell, K. , Millard, R. , Tan, A. , Kiss, G. , Ridder, D. , Everaert, K. , Keppenne, V. , Wyndaele, J. J. & 31 others Damiao, R., Bezerra, C. A., Noronha, J. A. P., Truzzi, J. C. C. I., Gajewski, J. B., Herschorn, S., Pommerville, P. J., Skehan, A., Steinhoff, G., Tu, L. M., Brodak, M., Janda, V., Krhut, J., Mecl, J., Student, V., Amarenco, G., Denys, P., Hamid, S. A., Soler, J. M., Hamann, M., Sievert, K. D., Beckers, G., Heesakers, J. P. F. A., Van Koeveringe, G., Blok, B., Tuckey, J., Ilkowski, J., Jablonska, Z., Kmieciak, R., Ruiz, H. E. & On Behalf of 191622-094 Investigators Feb 1 2017 In : Neurourology and Urodynamics. 36, 2, p. 368-375 8 p.

Research output: Contribution to journalArticle

Urinary Incontinence
Safety
Intermittent Urethral Catheterization
Therapeutics
Quality of Life
9 Citations

Emergence of mmpT5 variants during bedaquiline treatment of mycobacterium intracellulare lung disease

Alexander, D. C., Vasireddy, R., Vasireddy, S., Philley, J. V., Brown-Elliott, B. A., Perry, B. J., Griffith, D. E., Benwill, J. L., Cameron, A. D. S. & Wallace, R. J. Feb 1 2017 In : Journal of Clinical Microbiology. 55, 2, p. 574-584 11 p.

Research output: Contribution to journalArticle

bedaquiline
Mycobacterium avium Complex
Lung Diseases
Recurrence
Diarylquinolines

ENaCs as Both Effectors and Regulators of MiRNAs in Lung Epithelial Development and Regeneration

Ding, Y., Zhao, R., Zhao, X., Matthay, M. A., Nie, H. G. & Ji, H. L. Nov 27 2017 (Accepted/In press) In : Cellular Physiology and Biochemistry. p. 1120-1132 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Regeneration
Lung
Re-Epithelialization
Kidney

Exosomal miRNAs in nipple aspirate fluid and breast cancer

Qin, W., Zhang, K. & Sauter, E. R. Oct 1 2017 In : Translational Cancer Research. 6, p. S1304-S1310

Research output: Contribution to journalArticle

Nipple Aspirate Fluid
Exosomes
MicroRNAs
Breast Neoplasms
Celecoxib
1 Citations

Exosome secretome and mediated signaling in breast cancer patients with nontuberculous mycobacterial disease

Philley, J. V., Kannan, A., Griffith, D. E., Devine, M. S., Benwill, J. L., Wallace, R. J., Brown-Elliott, B. A., Thakkar, F., Taskar, V., Fox, J. G., Alqaid, A., Bains, H., Gupta, S. & Dasgupta, S. 2017 In : Oncotarget. 8, 11, p. 18070-18081 12 p.

Research output: Contribution to journalArticle

Exosomes
Extracellular Matrix Proteins
Breast Neoplasms
Coculture Techniques
Nontuberculous Mycobacteria

Exosomes in blood and cancer

Sauter, E. R. Oct 1 2017 In : Translational Cancer Research. 6, p. S1316-S1320

Research output: Contribution to journalReview article

Exosomes
Body Fluids
Neoplasms
RNA
Lipids

Exosomes in lymph and cancer

Sauter, E. R. Oct 1 2017 In : Translational Cancer Research. 6, p. S1311-S1315

Research output: Contribution to journalReview article

Exosomes
Lymph
Lymphatic Vessels
Subclavian Vein
Lymphatic System

Formulation for a novel inhaled peptide therapeutic for idiopathic pulmonary fibrosis

Hengsawas Surasarang, S., Florova, G., Komissarov, A. A., Shetty, S., Idell, S. & Williams, R. O. Nov 9 2017 (Accepted/In press) In : Drug Development and Industrial Pharmacy. p. 1-15 15 p.

Research output: Contribution to journalArticle

Trifluoroacetic Acid
Idiopathic Pulmonary Fibrosis
Lactose
Peptides
Excipients

Frequency of untreated hypogammaglobulinemia in bronchiectasis

Ruffner, M. A., Aksamit, T. R., Thomashow, B., Choate, R., DiMango, A., Turino, G. M., O'Donnell, A. E., Johnson, M. M., Olivier, K. N., Fennelly, K., Daley, C. L., Winthrop, K. L., Metersky, M. L., Salathe, M. A., Knowles, M. R., Daniels, M. L. A., Noone, P. G., Tino, G., Griffith, D. E. & Sullivan, K. E. Jul 1 2017 In : Annals of Allergy, Asthma and Immunology. 119, 1, p. 83-85 3 p.

Research output: Contribution to journalArticle

Agammaglobulinemia
Bronchiectasis

Future perspectives for body fluid exosomes and cancer

Sauter, E. R. Oct 1 2017 In : Translational Cancer Research. 6, p. S1394-S1397

Research output: Contribution to journalArticle

Exosomes
Body Fluids
Neoplasms
Early Detection of Cancer
Carbohydrates

Genetic Mutation and Exosome Signature of Human Papilloma Virus Associated Oropharyngeal Cancer

Kannan, A., Hertweck, K. L., Philley, J. V., Wells, R. B. & Dasgupta, S. Apr 6 2017 In : Scientific Reports. 7, 46102

Research output: Contribution to journalArticle

Papillomaviridae
Oropharyngeal Neoplasms
Exosomes
Human papillomavirus 16
Mutation

How exosomes in human breast milk may influence breast cancer risk

Sauter, E. R. & Reidy, D. Oct 1 2017 In : Translational Cancer Research. 6, p. S1384-S1388

Research output: Contribution to journalReview article

Exosomes
Human Milk
Breast Neoplasms
Body Fluids
Cell Communication

Human Milk and Matched Serum Demonstrate Concentration of Select miRNAs

Qin, W., Dasgupta, S., Corradi, J. & Sauter, E. R. Jan 1 2017 In : Breastfeeding Medicine. 12, 1, p. 63-66 4 p.

Research output: Contribution to journalArticle

Human Milk
MicroRNAs
Milk
Serum
Breast Neoplasms
1 Citations

Human myosin VIIa is a very slow processive motor protein on various cellular actin structures

Sato, O., Komatsu, S., Sakai, T., Tsukasaki, Y., Tanaka, R., Mizutani, T., Watanabe, T. M., Ikebe, R. & Ikebe, M. 2017 In : Journal of Biological Chemistry. 292, 26, p. 10950-10960 11 p.

Research output: Contribution to journalArticle

Cellular Structures
Actins
Inner Auditory Hair Cells
Proteins
Stress Fibers
10 Citations

IL-21-dependent expansion of memory-like NK cells enhances protective immune responses against Mycobacterium tuberculosis

Venkatasubramanian, S., Cheekatla, S., Paidipally, P., Tripathi, D., Welch, E., Tvinnereim, A. R., Nurieva, R. & Vankayalapati, R. Jul 1 2017 In : Mucosal Immunology. 10, 4, p. 1031-1042 12 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Natural Killer Cells
Bacterial Vaccines
Latent Tuberculosis
interleukin-21

IL-21 receptor signaling is essential for optimal CD4+ T cell function and control of mycobacterium tuberculosis infection in mice

Cheekatla, S. S., Tripathi, D., Venkatasubramanian, S., Paidipally, P., Welch, E., Tvinnereim, A. R., Nurieva, R. & Vankayalapati, R. Oct 15 2017 In : Journal of Immunology. 199, 8, p. 2815-2822 8 p.

Research output: Contribution to journalArticle

Interleukin-21 Receptors
Mycobacterium Infections
Mycobacterium tuberculosis
T-Lymphocytes
Knockout Mice
1 Citations

Inhibition of Glycogen Synthase Kinase 3β Blocks Mesomesenchymal Transition and Attenuates Streptococcus pneumonia–Mediated Pleural Injury in Mice

Boren, J., Shryock, G., Fergis, A., Jeffers, A., Owens, S., Qin, W., Koenig, K. B., Tsukasaki, Y., Komatsu, S., Ikebe, M., Idell, S. & Tucker, T. A. Nov 1 2017 In : American Journal of Pathology. 187, 11, p. 2461-2472 12 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinases
Streptococcus pneumoniae
Wounds and Injuries
Smooth Muscle
Actins
8 Citations

In vitro susceptibility testing of bedaquiline against Mycobacterium avium complex

Brown-Elliott, B. A., Philley, J. V., Griffith, D. E., Thakkar, F. & Wallace, R. J. Feb 1 2017 In : Antimicrobial Agents and Chemotherapy. 61, 2, e01798

Research output: Contribution to journalArticle

bedaquiline
Mycobacterium avium Complex
Rifampin
Cytochrome P-450 Enzyme System
Guidelines

In vitro susceptibility testing of tedizolid against isolates of Nocardia

Brown-Elliott, B. A. & Wallace, R. J. Dec 1 2017 In : Antimicrobial Agents and Chemotherapy. 61, 12, e01537

Research output: Contribution to journalArticle

Nocardia
Linezolid
Oxazolidinones
In Vitro Techniques
Nocardia Infections
6 Citations

In vitro susceptibility testing of tedizolid against nontuberculous mycobacteria

Brown-Elliott, B. A. & Wallace, R. J. Jun 1 2017 In : Journal of Clinical Microbiology. 55, 6, p. 1747-1754 8 p.

Research output: Contribution to journalArticle

Linezolid
Nontuberculous Mycobacteria
Oxazolidinones
In Vitro Techniques
Mycobacterium avium Complex

KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis

Kamata, H., Tsukasaki, Y., Sakai, T., Ikebe, R., Wang, J., Jeffers, A., Boren, J., Owens, S., Suzuki, T., Higashihara, M., Idell, S., Tucker, T. A. & Ikebe, M. Dec 1 2017 In : Scientific Reports. 7, 1, 4556

Research output: Contribution to journalArticle

Transport Vesicles
Myofibroblasts
Fibrosis
Collagen
Kinesin
1 Citations

Metalloproteinase-9 contributes to endothelial dysfunction in atherosclerosis via protease activated receptor-1

Florence, J. M., Krupa, A., Booshehri, L. M., Allen, T. C. & Kurdowska, A. K. Feb 1 2017 In : PLoS ONE. 12, 2, e0171427

Research output: Contribution to journalArticle

PAR-1 Receptor
Metalloproteases
metalloproteinases
atherosclerosis
Atherosclerosis

Mycobacterium grossiae sp. Nov., a rapidly growing, scotochromogenic species isolated from human clinical respiratory and blood culture specimens

Paniz-Mondolfi, A. E., Greninger, A. L., Ladutko, L., Brown-Elliott, B. A., Vasireddy, R., Jakubiec, W., Vasireddy, S., Wallace, R. J., Simmon, K. E., Dunn, B. E., Jackoway, G., Vora, S. B., Quinn, K. K., Qin, X. & Campbell, S. Nov 1 2017 In : International Journal of Systematic and Evolutionary Microbiology. 67, 11, p. 4345-4351 7 p.

Research output: Contribution to journalArticle

Mycobacterium
blood
Mycobacterium wolinskyi
Mycobacterium neoaurum
Mycobacterium aurum
2 Citations

Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation

He, K., Sakai, T., Tsukasaki, Y., Watanabe, T. M. & Ikebe, M. Dec 1 2017 In : Scientific Reports. 7, 1, 13685

Research output: Contribution to journalArticle

myosins
leading edges
elongation
adhesion
cycles
1 Citations

Novel mechanisms for crotonaldehyde-induced lung edema

Li, Y., Chang, J., Cui, Y., Zhao, R., Ding, Y., Hou, Y., Zhou, Z., Ji, H. L. & Nie, H. 2017 In : Oncotarget. 8, 48, p. 83509-83522 14 p.

Research output: Contribution to journalArticle

2-butenal
Edema
Epithelial Sodium Channels
Lung
Acute Lung Injury

Outcomes and costs of out-patient MDR-TB care in the USA

Marks, S. M., Hirsch-Moverman, Y., Seaworth, B., Salcedo, K., Graviss, E. A., Armstrong, L., Armitige, L., Flood, J. & Mase, S. Apr 1 2017 In : International Journal of Tuberculosis and Lung Disease. 21, 4, p. 477-478 2 p.

Research output: Contribution to journalLetter

Outpatients
Costs and Cost Analysis
3 Citations

p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis

Shetty, S. K., Tiwari, N., Marudamuthu, A. S., Puthusseri, B., Bhandary, Y. P., Fu, J., Levin, J., Idell, S. & Shetty, S. May 1 2017 In : American Journal of Pathology. 187, 5, p. 1016-1034 19 p.

Research output: Contribution to journalArticle

Pulmonary Fibrosis
Lung Injury
Idiopathic Pulmonary Fibrosis
Bleomycin
Apoptosis

Pathogenesis of pleural infection: A complex warfare

Popowicz, N., Idell, S. & Lee, Y. C. G. 2017 (Accepted/In press) In : Respirology.

Research output: Contribution to journalArticle

Infection
Warfare
8 Citations

Poor adherence to management guidelines in nontuberculous mycobacterial pulmonary diseases

Van Ingen, J., Wagner, D., Gallagher, J., Morimoto, K., Lange, C., Haworth, C. S., Floto, R. A., Adjemian, J., Prevots, D. R. & Griffith, D. E. Feb 1 2017 In : European Respiratory Journal. 49, 2, 1601855

Research output: Contribution to journalArticle

Empyema
Fibrinolysin
Thrombolytic Therapy
Pleural Effusion
Plasminogen Activators